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Children and Petit Sudden death oh been reported in affiliation with CNS incitant treatment at usual pondération in children and jeune with Structurel cardiac abnormalities pépite other serious heart problems. Although some serious heart problems alone carry an increased risk of sudden death, stimulant products generally should not Quand used in children pépite fils with known serious structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, or other serious cardiac problems that may rond-point them at increased vulnerability to the sympathomimetic effects of a incitant drug [see CONTRAINDICATIONS (4)].
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Celui dossier présente des fraîche pratiques nonobstant ceux-ci qui utilisent ceci médicament. Celui ne peut Chez négatif mésaventure remplacer les Note d'seul professionnel à l’égard de la santé.
Lisdexamfetamine dimesylate was not clastogenic in the mouse généreux marrow micronucleus expérience in vivo and was negative when tested in the E. coli and S. typhimurium components of the Ames épreuve and in the L5178Y/TK+- mouse lymphoma assay in vitro. Amphetamine (d- to l-enantiomer coefficient of 3:1) did not adversely affect fertility or early embryonic development in the rat at mesure of up to 20 mg/kg/day.
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Aggression Aggressive behavior pépite hostility is often observed in children and adolescents with ADHD, and eh been reported in clinical trials and the postmarketing experience of some medications indicated intuition the treatment of ADHD.
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